Hydrochloric Acid → HCID 71815305, compound

Participants

Reaction Conditions

Reaction Steps

6-(4-Morpholin-4-yl-phenyl)-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalen (0.21 g, 0.4 mmol) was dissolved in MeOH and treated with concentrated HCl (0.14 mL, 4.3 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 6-(4-Morpholin-4-yl-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.1 g, 0.3 mmol) as brown solid in 65% yield.

Provenance & Evidence