Benzenesulfonyl chloride → 5-Chloro-2-[2-[(benzenesulfonyl)oxy]ethyl]-7-[(2,4,6-trimethylphenyl)methoxy]anthra-[1,9-cd]pyrazol-6-(2H) one
Reaction equation
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH2:40][CH2:41][OH:42])[N:17]=[C:18]3[C:27]4[C:22](=[C:23]([O:28][CH2:29][C:30]5[C:35]([CH3:36])=[CH:34][C:33]([CH3:37])=[CH:32][C:31]=5[CH3:38])[CH:24]=[CH:25][CH:26]=4)[C:21](=[O:39])[C:20]=1[C:19]=23.ClC1C=CC2N(CCO)N=C3C4C(=CC=CC=4OCC4C(C)=CC(C)=CC=4C)C(=O)C=1C=23>>[Cl:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH2:40][CH2:41][O:42][S:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)(=[O:9])=[O:8])[N:17]=[C:18]3[C:27]4[C:22](=[C:23]([O:28][CH2:29][C:30]5[C:35]([CH3:36])=[CH:34][C:33]([CH3:37])=[CH:32][C:31]=5[CH3:38])[CH:24]=[CH:25][CH:26]=4)[C:21](=[O:39])[C:20]=1[C:19]=23Participants
4
Reactant 3
Product 1
Procedure
Starting with benzenesulfonyl chloride and the mixture of regioisomers of 5-chloro-2-(2-hydroxyethyl)-7-[(2,4,6-trimethylphenyl)methoxy]anthra-[1,9-cd]pyrazol-6(2H)-one II and 5-chloro-2-(2-hydroxyethyl)-10-[(2,4,6-trimethylphenyl) methoxy]anthra-[1,9-cd]pyrazol-6(2H)-one III, using the procedure of example 3, the title compound was prepared.
Sources & evidence
- ORD record
- ord-2cfee49587a7491f9b68ddf95299674a
- Source dataset
- uspto-grants-1997_04
- Patent number
- US05618944
Reaction notes
Loading…