HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Indanyl isocyanate → 1-Cyclopentyl-3-indan-5-yl-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Indanyl isocyanate | HCID 5003681 | — |
| Reactant | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Product | 1-Cyclopentyl-3-indan-5-yl-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 67249060 | 49.1% |
Reaction Steps
1-Cyclopentyl-3-indan-5-yl-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione (21 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 5-isocyanato-indan (0.5 mmol) following general procedure C. LCMS: m/z 428 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853226B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-a78344e5b86c46559e987f6520b84cec |
| Source note | uspto-grants-2014_10 |