Phenethylamine → [(2-Phenylethyl)amino]acetonitrile

Participants

Reaction Conditions

Reaction Steps

Chloro-acetonitrile (1.5) eq was added to a solution of phenethylamine (1 eq) and K2CO3 (2 eq) in CH3CN. The mixture was stirred at 60° C. for 4 hrs. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure. Purification by flash chromatography gave the expected compound.

Provenance & Evidence