反应详情

温度

65 °C

Ethyl 1H-indole-2-carboxylate (2.953 g) and cyclohex-2-enone (1.004 mL) were added to acetonitrile (50 mL). Bismuth (III) trifluoromethanesulfonate (341 mg) was added, and the solution was heated at 65° C. for two days. The solution was cooled, concentrated, and purified by flash column chromatography on silica gel with 10% increasing to 20% ethyl acetate in hexanes to provide the title compound.

1. temperatureThe solution was cooled
2. concentrationconcentrated
3. custompurified by flash column chromatography on silica gel with 10%
4. temperatureincreasing to 20% ethyl acetate in hexanes