HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 59544866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 59544864 | HCID 59544864 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 59544866 | HCID 59544866 | 85.6% |
Reaction Steps
To 1-nitro-4-(4-(trifluoromethyl)phenethylsulfonyl)benzene (3.99 g, 0.0111 mol) in methanol (84 mL, 2.1 mol) under argon was added 10% palladium on carbon. The reaction mixture was stirred under hydrogen overnight, filtered over Celite, concentrated and purified on silica gel (hexane-EtOAc) to give 3.13 g of a white solid. LCMS: M+330.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853250B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-31dc1eb9668d4d03b766042869e1b7c1 |
| Source note | uspto-grants-2014_10 |