HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Methyl 3-iodo-4-oxo-1,4-dihydroquinoline-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | Methyl 4-hydroxyquinoline-6-carboxylate | HCID 16112715 | — |
| Solvent | Water | HCID 962 | — |
| Product | Methyl 3-iodo-4-oxo-1,4-dihydroquinoline-6-carboxylate | HCID 67773905 | 111.9% |
Reaction Steps
To a mixture of methyl 4-oxo-1,4-dihydroquinoline-6-carboxylate (1.1 g) and acetic acid (30 mL) was added N-iodosuccinimide (1.1 g), followed by stirring at room temperature for one day. The reaction mixture was diluted with water, and the precipitate was collected by filtration to obtain methyl 3-iodo-4-oxo-1,4-dihydroquinoline-6-carboxylate (1.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853242B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-5ce70bb9aed241c8bc8f1900aae8b498 |
| Source note | uspto-grants-2014_10 |