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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 533451Generated: October 28, 2026

HCID 58098661, compound → HCID 58098778, compound

https://huagongshe.com/reaction/533451

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58098661HCID 58098661—
ReactantHCID 178418250HCID 178418250—
SolventWaterHCID 962—
SolventAcetonitrileHCID 6342—
ProductHCID 58098778HCID 580987786.8%

Reaction Steps

To a mixture of 2-(3-acetamidophenylamino)-4-(piperidin-3-ylmethylamino)pyrimidine-5-carboxamide (40 mg, 0.104 mmol) in CH3CN (2 mL), a solution of KOCN (50 mg, 0.617 mmol) in H2O (1 mL) was added. The mixture was stirred at 70 C for 4 h. It was then purified by HPLC to give the titled compound (3 mg). MS 427.4 (M+H); UV 202.2, 248.6 nm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853230B2
Source datasetuspto-grants-2014_10
ORD IDord-242c1227259e4a71b67c7a25c975d802
Source noteuspto-grants-2014_10