HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58098829, compound → HCID 49800542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58098829 | HCID 58098829 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 49800542 | HCID 49800542 | 59.2% |
Reaction Steps
A solution of tert-butyl 4-((2-(3-acetamidophenylamino)-5-carbamoylpyrimidin-4-ylamino)methyl)piperidine-1-carboxylate (100 mg, 0.207 mmol) in TFA (3 mL) was stirred at room temperature for 30 min. TFA was removed in vacuo. The residue was purified by HPLC to give the titled compound (47 mg). MS 384.4 (M+H); UV 200.0, 248.6 nm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853230B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-101ec339786744f1bda348a4ce175228 |
| Source note | uspto-grants-2014_10 |