HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide → N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098809 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098633 | 98.4% |
Reaction Steps
To a solution of N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (430 mg) in EtOH (10 mL) was added Pd/C (200 mg) and was charged with H2 (1 atm). After stirring for 3 h, Pd/C was removed by filtration and the filtrate was concentrated to give N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (380 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853230B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-ac31356535b24681a9fd13f7ba9590fd |
| Source note | uspto-grants-2014_10 |