HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-(Ethylthio)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-(Ethylsulfanyl)benzoic acid | HCID 425758 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-(Ethylthio)benzoyl chloride | HCID 14853175 | 100% |
Reaction Steps
To a mixture of 2-ethylsulfanylbenzoic acid (9.11 g), chloroform (100 ml), and oxalyl chloride (9.72 g), DMF (2 drops) was added, and stirred at room temperature for 6 hours. The reaction mixture was concentrated under reduced pressure to give 10.03 g of 2-ethylsulfanylbenzoic acid chloride (Compound (1H)-241).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853238B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-8d4b998dbd6649999510899b31db47f7 |
| Source note | uspto-grants-2014_10 |