HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → HCID 11584767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- | HCID 11325 | — |
| Reactant | 1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol | HCID 23992385 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 11584767 | HCID 11584767 | 51.8% |
Reaction Steps
Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0916 g, 0.312 mmol) and 2-(2-bromoethyl)-1H-isoindole-1,3(2H)-dione (0.130 g, 0.512 mmol) in 2 CH3CN/3 CHCl3 (4.0 mL) were reacted to give the desired product (0.0881 g, 51.8%). EI-MS m/z 467(M+) Rt (1.91 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853404B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-520978deffd14254a38a94374d671f7a |
| Source note | uspto-grants-2014_10 |