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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 533799Generated: October 29, 2026

1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → HCID 11584767, compound

https://huagongshe.com/reaction/533799

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 11325—
Reactant1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanolHCID 23992385—
SolventAcetonitrileHCID 6342—
ProductHCID 11584767HCID 1158476751.8%

Reaction Steps

Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0916 g, 0.312 mmol) and 2-(2-bromoethyl)-1H-isoindole-1,3(2H)-dione (0.130 g, 0.512 mmol) in 2 CH3CN/3 CHCl3 (4.0 mL) were reacted to give the desired product (0.0881 g, 51.8%). EI-MS m/z 467(M+) Rt (1.91 min).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853404B2
Source datasetuspto-grants-2014_10
ORD IDord-520978deffd14254a38a94374d671f7a
Source noteuspto-grants-2014_10