2-Cyclopropylethan-1-ol → HCID 86715096, compound

HRID 533905Notes

Reaction equation

HRID 533905 reaction equation
[OH:1][C:2]1[CH:14]=[CH:13][C:5]([O:6][C@@H:7]2[CH2:11][CH2:10][NH:9][C:8]2=[O:12])=[CH:4][CH:3]=1.[CH:15]1([CH2:18][CH2:19]O)[CH2:17][CH2:16]1>>[CH:15]1([CH2:18][CH2:19][O:1][C:2]2[CH:14]=[CH:13][C:5]([O:6][C@@H:7]3[CH2:11][CH2:10][NH:9][C:8]3=[O:12])=[CH:4][CH:3]=2)[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 1376422-Cyclopropylethan-1-olHCID 86715097HCID 86715097, compound

Product 1

HCID 86715096HCID 86715096, compound

Procedure

Typical Procedure 3 was followed. Reaction of (R)-3-(4-hydroxy-phenoxy)-pyrrolidin-2-one with 2-cyclopropyl-ethanol provided the title compound. MS ESI+: m/z=262 [M+H]+.

Sources & evidence

ORD record
ord-eacadd34122447d6a544345c8b5609c3
Source dataset
uspto-grants-2014_10
Patent number
US08853412B2

Reaction notes

Loading…