2-Bromo-5-hydroxypyridine → HCID 86715100, compound

HRID 533909Notes

Reaction equation

HRID 533909 reaction equation
[OH:1][C@H:2]1[CH2:6][CH2:5][NH:4][C:3]1=[O:7].[Br:8][C:9]1[N:14]=[CH:13][C:12](O)=[CH:11][CH:10]=1>>[Br:8][C:9]1[N:14]=[CH:13][C:12]([O:1][C@@H:2]2[CH2:6][CH2:5][NH:4][C:3]2=[O:7])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 27628652-Bromo-5-hydroxypyridineHCID 11029774(3S)-3-hydroxypyrrolidin-2-one

Product 1

HCID 86715100HCID 86715100, compound

Procedure

Typical Procedure 3 was followed. Reaction of (S)-3-hydroxy-pyrrolidin-2-one with 6-bromo-pyridin-3-ol provided the subtitle compound. MS ESI+: m/z=257 [M+H]+.

Sources & evidence

ORD record
ord-2cb5f3d849c844499bb006a22ddd4e48
Source dataset
uspto-grants-2014_10
Patent number
US08853412B2

Reaction notes

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