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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 533910Generated: October 30, 2026

Lithium thioethoxide → (R)-3-(6-Ethylsulfanyl-pyridin-3-yloxy)-pyrrolidin-2-one

https://huagongshe.com/reaction/533910

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium thioethoxideHCID 10866251—
ReactantHCID 86715100HCID 86715100—
Product(R)-3-(6-Ethylsulfanyl-pyridin-3-yloxy)-pyrrolidin-2-oneHCID 86715101—

Reaction Steps

Typical Procedure 8 was followed. Reaction of (R)-3-(6-bromo-pyridin-3-yloxy)-pyrrolidin-2-one with lithium ethanethiolate provided the title compound. MS ESI+: m/z=239 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853412B2
Source datasetuspto-grants-2014_10
ORD IDord-0854ffef2d6e40aea6fd50bc6bba0208
Source noteuspto-grants-2014_10