HCID 86715121, compound → HCID 86715120, compound

HRID 533934Notes

Reaction equation

HRID 533934 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH3:13])[C:5]([O:8][CH2:9][CH:10]2[CH2:12][CH2:11]2)=[N:6][CH:7]=1.B([O-])[O-:15]>>[CH:10]1([CH2:9][O:8][C:5]2[N:6]=[CH:7][C:2]([OH:15])=[CH:3][C:4]=2[CH3:13])[CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 86715121HCID 86715121, compoundHCID 178514824HCID 178514824, compound

Product 1

HCID 86715120HCID 86715120, compound

Procedure

Following Typical Procedures 4 and 5a, conversion of 5-bromo-2-cyclopropylmethoxy-3-methyl-pyridine to the boronate and oxidation with NaBO3 provided the title compound. MS ESI+: m/z=180 [M+H]+.

Sources & evidence

ORD record
ord-4480b9bfaebf401990985fd2ee8da141
Source dataset
uspto-grants-2014_10
Patent number
US08853412B2

Reaction notes

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