HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19962312, compound → 4-[(7,8-Dihydro-8,8-dimethyl-5-phenylthionaphth-3-yl)ethynyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19962312 | HCID 19962312 | — |
| Reactant | HCID 19962313 | HCID 19962313 | — |
| Reactant | Ethyl 4-[(7,8-dihydro-8,8-dimethyl-5-phenylthionaphth-3-yl)ethynyl]benzoate | HCID 19962320 | — |
| Product | 4-[(7,8-Dihydro-8,8-dimethyl-5-phenylthionaphth-3-yl)ethynyl]benzoic acid | HCID 19962314 | — |
Reaction Steps
Employing the same general procedure as for the preparation of 4-[(7,8-dihydro-8,8-dimethyl-5-ethylthionaphth-3-yl)ethynyl]benzoic acid (Compound 153), 100 mg (0.38 mmol) of ethyl 4-[(7,8-dihydro-8,8-dimethyl-5-phenylthionaphth-3-yl)ethynyl]benzoate (Compound 155) was converted into the title compound (white solid, recrystallized from acetonitrile) using 2 ml of KOH (2N aqueous solution).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618931 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-4c7d3697045b4fb4b1b262c95d9f48a3 |
| Source note | uspto-grants-1997_04 |