HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-[[3-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]propyl]amino]-pyrimidine-4-carboxylate → HCID 178418571, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-[[3-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]propyl]amino]-pyrimidine-4-carboxylate | HCID 19013272 | — |
| Reactant | HCID 178418575 | HCID 178418575 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 178418571 | HCID 178418571 | — |
Reaction Steps
1.89 g of (4.5 mmols) of methyl 2-[[3-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]propyl]amino]-pyrimidine-4-carboxylate and 0.77 g (5 mmols) of 2-[(2-aminoethyl)amino]pyrimidin-4(1H)-one in 5 ml of n-butanol are introduced into a 25 ml, round bottomed flask. The mixture is heated at the reflux temperature of the solvent for 15 hours and then the solvent is evaporated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05244894 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-682b7c7c9d9d4c65b29faad31f704d69 |
| Source note | uspto-grants-1993_09 |