Potassium Hydroxide → 1H-Perfluorohexane

Participants

Reaction Steps

Into a 1 l four-necked flask equipped with a stirrer, a distillation apparatus-equipped reflux condenser, a dropping funnel and a thermometer, 400 cc of isopropyl alcohol, 49.5 g (0.75 mol) of 85% potassium hydroxide and 1 g of tetrabutylphosphonium bromide were charged. The reactor was heated to bring the internal temperature to 60° C. Then, 223 g (0.5 mol) of C6F13I was dropwise added thereto over a period of one hour. After completion of the dropwise addition, heating and refluxing were continued for one hour. The conversion at that time was 100%. A fraction with a boiling point of up to 75° C. was recovered by distillation from the reactor. The recovered liquid was washed five times with 200 g of water, and acetone and isopropyl alcohol were removed. Thus, 152 g of C6F13H having a purity of 99.9%, was obtained.

Provenance & Evidence