HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 17beta-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 17beta-benzoyl-estra-1,3,5(10)-triene-3-carboxylate | HCID 54345982 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 17beta-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic Acid | HCID 9886601 | — |
Reaction Steps
A mixture of methyl 17β-benzoyl-estra-1,3,5(10)-triene-3-carboxylate, K2CO3, water and methanol is heated at reflux for about 5 hours. Acidifications followed by conventional workup yields title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618806 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-01ec06511c56483e9ef67f1fc79fd4d2 |
| Source note | uspto-grants-1997_04 |