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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 53450Generated: October 30, 2026

Water → 17beta-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic Acid

https://huagongshe.com/reaction/53450

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl 17beta-benzoyl-estra-1,3,5(10)-triene-3-carboxylateHCID 54345982—
SolventMethanolHCID 887—
Product17beta-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic AcidHCID 9886601—

Reaction Steps

A mixture of methyl 17β-benzoyl-estra-1,3,5(10)-triene-3-carboxylate, K2CO3, water and methanol is heated at reflux for about 5 hours. Acidification followed by conventional workup yields title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05618806
Source datasetuspto-grants-1997_04
ORD IDord-c0049b101cae4cfb9bd955f41eef4648
Source noteuspto-grants-1997_04