HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (R)-N-Benzyl-2-acetamido-3-hydroxypropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 44579179 | HCID 44579179 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (R)-N-Benzyl-2-acetamido-3-hydroxypropionamide | HCID 10889901 | 52% |
Reaction Steps
To a solution of N-benzyl-O-tert-butyl-N2-acetyl-D-serinamide (0.5 g) and dichloromethane (10 mL), aq. HCl 35% (5 mL) was added. The solution was stirred for 2 hours at room temperature for completion of reaction and after workup and crystallization gave solid 0.21 g N-benzyl-N2-acetyl-D-serinamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853439B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-cf2717e26499467c82522df727372b1b |
| Source note | uspto-grants-2014_10 |