Hydroquinone → HCID 67134284, compound

Participants

Reaction Steps

3.24 g (60 mmol) of butadiene were condensed at −78° C. into an autoclave under a nitrogen atmosphere. 2.03 g (10 mmol) of 3,4,5-trifluoro-β-nitrostyrene from example 2.2 dissolved in 6 ml of toluene and 30 mg of hydroquinone were added. A nitrogen atmosphere was applied (120 bar) and the suspension was heated for 12 h to 130° C. The reaction mixture was expanded and all volatiles were evaporated in vacuo. Column chromatography (SiO2, cyclohexane/ethylacetate 9:1) yielded 2.4 g (9.4 mmol, 94% of theory) of the title compound as yellowish crystals.

Provenance & Evidence