HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(3-bromo-5-(trifluoromethyl)phenyl)ethanone → 2-(3-Bromo-5-(trifluoromethyl)phenyl)-2-oxoethyl methyl succinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(3-bromo-5-(trifluoromethyl)phenyl)ethanone | HCID 19702334 | — |
| Reactant | 2-(3-Chloro-5-(trifluoromethyl)phenyl)-2-oxoethyl methyl succinate | HCID 66750879 | — |
| Product | 2-(3-Bromo-5-(trifluoromethyl)phenyl)-2-oxoethyl methyl succinate | HCID 66751127 | 60% |
Reaction Steps
The title compound was prepared from 2-bromo-1-(3-bromo-5-(trifluoromethyl)phenyl)ethanone (Reference Example 42) by a procedure similar to the one described for 2-(3-chloro-5-(trifluoromethyl)phenyl)-2-oxoethyl methyl succinate (Reference Example 35) to provide 2-(3-bromo-5-(trifluoromethyl)phenyl)-2-oxoethyl methyl succinate (16.05 g, 60%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853215B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-44c7431feb7a4b6d8a793a9b81cdb3ee |
| Source note | uspto-grants-2014_10 |