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HRID534866

反应详情

EQUATION

反应方程式

HRID 534866 的结构方程式

REACTANTS

反应物

2
反应SMILES：COC(=O)CCc1nc(-c2cc(C(C)=O)cc(C(F)(F)F)c2)co1
HCID66750826

未命名化合物

反应SMILES：O=C(O)CCc1nc(-c2cc(Cl)cc(C(F)(F)F)c2)co1
HCID66751118

未命名化合物

PRODUCTS

产物

1
反应SMILES：CC(=O)c1cc(-c2coc(CCC(=O)O)n2)cc(C(F)(F)F)c1
HCID66750853

未命名化合物

收率 70%

PROCEDURE

实验过程

The title compound was prepared from methyl 3-(4-(3-acetyl-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoate (Reference Example 51) by a procedure similar to the one described for 3-(4-(3-chloro-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoic acid (Reference example 52) to provide 3-(4-(3-acetyl-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoic acid (0.081 g, 70%) as a white solid.