HCID 66751075, compound → HCID 66792759, compound

Participants

Reaction Steps

A mixture of N-[4-(benzyloxy)phenyl]-2-[4-(2-tert-butylphenyl)piperazin-1-yl]-2-oxoacetamide (Example 198, 3.64 g, 7.72 mmol) and palladium (10% on carbon, wetted with ca. 50% water, 300 mg) in ethyl acetate (10 mL) was stirred at room temperature for 24 h under hydrogen. The reaction mixture was diluted with tetrahydrofuran and filtered. The filtrate was concentrated under reduced pressure to give the title compound (2.90 g, 98%) as a white solid.

Provenance & Evidence