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HRID535080

反应详情

EQUATION

反应方程式

HRID 535080 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@H]1C[C@H](OC)CN(Cc2ccccc2)[C@@H]1C(=O)OCc1ccccc1
HCID131731930

未命名化合物

结构：[H][H]
HCID178418361

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H]1C[C@H](OC)CN[C@@H]1C(=O)O
HCID67305316

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of 2-benzyl 3-methyl (2S,3S,5S)-1-benzyl-5-methoxypiperidine-2,3-dicarboxylate (30.0 mg, 0.0000755 mol) in 2 mL of MeOH was hydrogenated in the presence of 10% Pd/C, under a balloon pressure of hydrogen, for 1 h. The catalyst was filtered off and the filtration was concentrated to dry. The residue was used directly in next step (16 mg, 97.6%). MS (ESI): (M+H)+=218.0.

WORKUP

后处理

  1. filtrationThe catalyst was filtered off
  2. filtrationthe filtration
  3. concentrationwas concentrated
  4. customto dry