HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenol → 3-{4-[1-(4-Trifluoromethylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenol | HCID 67874 | — |
| Reactant | Cyclobutane-1,1-diyldimethanol | HCID 4498243 | — |
| Reactant | Methyl 3-(4-hydroxyphenyl)hex-4-ynoate | HCID 57835749 | — |
| Product | 3-{4-[1-(4-Trifluoromethylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acid | HCID 56592286 | — |
Reaction Steps
Analogously to example 1, cyclobutane-1,1-diyldimethanol, 4-hydroxybenzotrifluoride and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-{4-[1-(4-trifluoromethylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859494B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-23f6976eeb124b4eb1642fda105f4f05 |
| Source note | uspto-grants-2014_10 |