Phenol → HCID 56592288, compound
Reaction equation
[C:1]1([CH2:7][OH:8])([CH2:5][OH:6])[CH2:4][CH2:3][CH2:2]1.[C:9]1(O)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.O[C:17]1[CH:22]=[CH:21][C:20]([CH:23]([C:29]#[C:30][CH3:31])[CH2:24][C:25]([O:27]C)=[O:26])=[CH:19][CH:18]=1>>[O:6]([CH2:5][C:1]1([CH2:7][O:8][C:17]2[CH:22]=[CH:21][C:20]([CH:23]([C:29]#[C:30][CH3:31])[CH2:24][C:25]([OH:27])=[O:26])=[CH:19][CH:18]=2)[CH2:4][CH2:3][CH2:2]1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1Participants
4
Procedure
Analogously to example 1, cyclobutane-1,1-diyldimethanol, phenol and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-[4-(1-phenoxymethylcyclobutylmethoxy)phenyl]hex-4-ynoic acid.
Sources & evidence
- ORD record
- ord-d3638c4127f44ee4b86668441c418a45
- Source dataset
- uspto-grants-2014_10
- Patent number
- US08859494B2
Reaction notes
Loading…