HCID 71145304, compound → HCID 71145793, compound

Participants

Reaction Steps

To a solution of (4-bromo-phenyl)-(8-thia-bicyclo[3.2.1]oct-3-yl)-methanol (1.99 g, 6.35 mmol) in DCM (100 ml) was added a total of manganese dioxide (8.28 g, 95.2 mmol) at RT and the reaction mixture was stirred for 24 hrs. The suspension was filtered and the residue was washed with DCM, dried in vacuo to yield the title intermediate (1.87 g, 5.83 mmol, 92%) as a colourless solid.

Provenance & Evidence