HCID 71145454, compound → HCID 86718438, compound

Participants

Reaction Steps

To a solution of (4-Bromo-phenyl)-(9-thia-bicyclo[3.3.1]non-3-yl)-methanol (1.10 g, 3.38 mmol) in DCM (53 ml) was added a total of manganese dioxide (4.88 g, 56.131 mmol) at RT and the reaction mixture was stirred for 24 hrs. The suspension was filtered through a pad of hyflo and the residue was washed with DCM, dried in vacuo to yield the title intermediate (880 mg, 2.57 mmol, 95%) as a beige solid.

Provenance & Evidence