9-Thiabicyclo[3.3.1]nonan-3-one → HCID 86718440, compound

Participants

Reaction Steps

A solution of sodium bis(trimethylsilyl)amide 1M in THF (37.9 ml, 37.9 mmol) was added dropwise to a suspension of (methoxymethyl)triphenylphosphonium chloride (13.40 g, 37.9 mmol) in THF (60 ml) at −10° C., followed by the addition of 9-thia-bicyclo[3.3.1]nonan-3-one (3.95 g, 25.3 mmol) at −10° C. The suspension was allowed to warm to Rt and stirring was continued for 16 hrs.

Provenance & Evidence