HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → 3-Iodo-7-methyl-2-pyridin-4-ylimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 7-Methyl-2-pyridin-4-ylimidazo[1,2-a]pyridine | HCID 86694392 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Iodo-7-methyl-2-pyridin-4-ylimidazo[1,2-a]pyridine | HCID 86694387 | — |
Reaction Steps
A mixture of 7-methyl-2-pyridin-4-ylimidazo[1,2-a]pyridine (6.52 g, 31.1 mmol), N-iodosuccinimide (7.0 g, 31.1 mmol) and ACN (180 ml) is stirred at RT for 17 h. The precipitate is collected, washed with ACN and dried. Yield: 4.4 g (42%). HPLC-MS: M+H=336; tR=1.55 min (*Method—3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859541B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-02b0edd80f884fd48c811471739774dc |
| Source note | uspto-grants-2014_10 |