反应详情

The product of Example 1B and 2-(3,5-difluorophenyl)acetic acid were treated using a method similar to that described in Example 10C to give the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.55 (s, 1H), 8.31 (dd, J=7.9, 1.3 Hz, 1H), 8.02 (d, J=1.3 Hz, 1H), 7.96-8.01 (m, 1H), 7.88-7.92 (m, 1H), 7.09-7.21 (m, 3H), 3.80-3.83 (m, 4H), 3.73 (s, 2H), 3.08-3.10 (m, 4H); MS (APCI+) M/Z 401 (M+H)+.