[(1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl]acetic acid → HCID 70975752, compound

Participants

Reaction Steps

The product from Example 10B and 2-((1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl)acetic acid was processed using a method similar to that described in Example 10C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.31 (s, 1H), 8.41 (dd, J=7.8, 1.4 Hz, 1H), 8.18 (d, J=8.0 Hz, 1H), 7.92-8.10 (m, 2H), 7.80 (dd, J=5.1, 1.1 Hz, 1H), 7.65 (dd, J=3.6, 1.1 Hz, 1H), 7.29 (dd, J=5.1, 3.6 Hz, 1H), 6.23 (dd, J=5.7, 3.0 Hz, 1H), 6.07 (dd, J=5.7, 2.8 Hz, 1H), 2.89-2.92 (m, 1H), 2.77-2.81 (m, 1H), 2.42-2.50 (m, 1H), 2.10 (dd, J=14.3, 7.9 Hz, 1H), 2.08 (dd, J=14.1, 8.0 Hz, 1H), 1.91 (ddd, J=11.5, 9.0, 3.8 Hz, 1H), 1.34-1.37 (m, 1H), 1.27 (d, J=8.1 Hz, 1H), 0.61 (ddd, J=11.5, 4.3, 2.5 Hz, 1H); MS (APCI) M/Z 392 (M+H)+.

Provenance & Evidence