2-((1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl)acetic acid → HCID 70975747, compound

Participants

Reaction Steps

The product from Example 14B and 2-((1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl)acetic acid was processed using a method similar to that described in Example 10C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.31 (s, 1H), 8.38-8.40 (m, 1H), 7.89-8.05 (m, 2H), 7.72 (d, J=5.1 Hz, 1H), 7.62-7.65 (m, 1H), 7.12 (d, J=5.1 Hz, 1H), 6.22 (dd, J=5.7, 3.0 Hz, 1H), 6.06 (dd, J=5.7, 2.8 Hz, 1H), 2.88-2.90 (m, 1H), 2.77-2.79 (m, 1H), 2.42-2.52 (m, 1H), 2.10 (s, 3H), 2.08 (m, 2H), 1.90 (ddd, J=11.5, 9.1, 3.7 Hz, 1H), 1.33-1.36 (m, 1H), 1.26 (d, J=8.0 Hz, 1H), 0.60 (ddd, J=11.5, 4.3, 2.5 Hz, 1H); MS (APCI) M/Z 392 (M+H)+.

Provenance & Evidence