4-Chlorophenylacetyl chloride → 2-(4-chlorophenyl)-N-[4-(2-chloropyridin-4-yl)-1-oxophthalazin-2(1H)-yl]acetamide

Participants

Reaction Steps

The product from Example 29B and 2-(4-chlorophenyl)acetyl chloride were processed using a method similar to that described in Example 4C to give the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 11.79 (s, 1H), 8.62 (d, J=5.0 Hz, 1H), 8.40-8.44 (m, 1H), 7.94-8.05 (m, 2H), 7.73-7.81 (m, 2H), 7.68 (dd, J=5.0, 1.5 Hz, 1H), 7.36-7.45 (m, 4H), 3.72 (s, 2H); MS (APCI+) M/Z 425 (M+H)+.

Provenance & Evidence