4-Toluenesulfonyl chloride → HCID 70975995, compound

Participants

Reaction Steps

The product from Example 42 and 4-methylbenzene-1-sulfonyl chloride were processed using a method similar to that described in Example 4C to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.53-11.64 (bs, 1H), 8.19-8.33 (bs, 1H), 8.23 (ddd, J=7.8, 1.5, 0.6 Hz, 1H), 8.06 (ddd, J=8.1, 1.4, 0.7 Hz, 1H), 7.95 (ddd, J=8.0, 7.2, 1.5 Hz, 1H), 7.87 (ddd, J=7.9, 7.2, 1.3 Hz, 1H), 7.57-7.61 (m, 2H), 7.33-7.49 (m, 4H), 7.21-7.25 (m, 2H), 4.22-4.24 (m, 2H), 3.69 (s, 2H), 2.31 (s, 3H); MS (ESI+) M/Z 497 (M+H)+.

Provenance & Evidence