Trifluoroacetic acid → HCID 71467867, compound

Participants

Reaction Steps

The product from Example 103C (23 mg, 0.043 mmol) in CH2Cl2 (4 mL) was treated with TFA (1 mL). The reaction mixture was stirred at room temperature for 20 minutes, concentrated, and the resulting residue was purified by HPLC (conditions from Example 10C) to afford 9.3 mg (50%) of the title compound. 1H NMR (400 MHz, DMSO-d6) δ 11.56 (s, 1H), 8.31 (dd, J=7.9, 0.9, 1H), 8.12 (d, J=7.8, 1H), 8.06-7.98 (m, 1H), 7.97-7.89 (m, 1H), 7.46-7.36 (m, 2H), 7.34-7.28 (m, 2H), 7.24-7.15 (m, 2H), 6.64-6.56 (m, 2H), 3.63 (s, 2H); MS (APCI+) M/Z 437 (M+H)+.

Provenance & Evidence