(2S)-2-((methoxycarbonyl)amino)-3-methylbutanoic acid → HCID 123459772, compound

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Reaction Steps

The product of Example 42 and (S)-2-(methoxycarbonylamino)-3-methylbutanoic acid were treated using a method similar to that described in Example 56 to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.59-11.62 (bs, 1H), 8.53 (d, J=5.5 Hz, 1H), 8.32 (dd, J=7.5, 1.7 Hz, 1H), 8.03 (d, J=7.1 Hz, 1H), 7.88-7.99 (m, 2H), 7.37-7.45 (m, 4H), 7.09-7.13 (m, 1H), 4.52-4.67 (m, 2H), 3.78-3.86 (m, 1H), 3.67 (s, 2H), 3.51 (s, 3H), 1.85-1.96 (m, 1H), 0.71-0.83 (d, 6H); MS (ESI+) M/Z 500 (M+H)+.

Provenance & Evidence