4-chlorophthalazin-1(2H)-one → 4-(2-ethylmorpholino)phthalazin-1(2H)-one

HRID 535627Notes

Reaction equation

HRID 535627 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5](=[O:12])[NH:4][N:3]=1.[CH2:13]([CH:15]1[O:20][CH2:19][CH2:18][NH:17][CH2:16]1)[CH3:14]>>[CH2:13]([CH:15]1[CH2:16][N:17]([C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5](=[O:12])[NH:4][N:3]=2)[CH2:18][CH2:19][O:20]1)[CH3:14]

Participants

3

Reactant 2

HCID 27751424-chlorophthalazin-1(2H)-oneHCID 149332062-Ethylmorpholine

Product 1

HCID 709760244-(2-ethylmorpholino)phthalazin-1(2H)-one

Procedure

4-chlorophthalazin-1(2H)-one and 2-ethylmorpholine were processed using a method similar to that described in Example 1A to afford the title compound. MS (APCI+) M/Z 260 (M+H)+.

Sources & evidence

ORD record
ord-ea3d5c63f03a421f9d35d5bae1d35127
Source dataset
uspto-grants-2014_10
Patent number
US08859549B2

Reaction notes

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