4-Chlorophenylacetyl chloride → HCID 70976263, compound

Participants

Reaction Steps

The product from Example 220B and (4-chlorophenyl)acetyl chloride were processed using a method similar to that described in Example 4C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.48 (s, 1H), 8.29 (dd, J=7.8, 1.2 Hz, 1H), 7.96-8.03 (m, 2H), 7.90 (ddd, J=7.9, 6.7, 1.4 Hz, 1H), 7.40-7.41 (m, 4H), 3.91 (dd, J=11.1, 2.6 Hz, 1H), 3.79 (td, J=11.4, 2.3 Hz, 1H), 3.67 (s, 2H), 3.56-3.65 (m, 1H), 3.26-3.32 (m, 2H), 2.76-2.84 (m, 1H), 2.51-2.57 (m, 1H), 1.48 (p, J=7.1 Hz, 2H), 0.92 (t, J=7.4 Hz, 3H); MS (DCI+) M/Z 427 (M+H)+, 444 (M+NH4)+.

Provenance & Evidence