HCID 59636708, compound → HCID 59636722, compound

HRID 535669Notes

Reaction equation

HRID 535669 reaction equation
[CH3:1][N:2]([CH3:20])[C:3]([C:5]1[O:6][C:7]2[C:13]([N:14]3[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)=[CH:12][CH:11]=[CH:10][C:8]=2[CH:9]=1)=[O:4].CC1C=CC(S(O[CH2:32][CH2:33][C:34]2[C:39]([O:40][CH3:41])=[CH:38][CH:37]=[CH:36][N:35]=2)(=O)=O)=CC=1>>[CH3:41][O:40][C:39]1[C:34]([CH2:33][CH2:32][N:17]2[CH2:18][CH2:19][N:14]([C:13]3[C:7]4[O:6][C:5]([C:3]([N:2]([CH3:20])[CH3:1])=[O:4])=[CH:9][C:8]=4[CH:10]=[CH:11][CH:12]=3)[CH2:15][CH2:16]2)=[N:35][CH:36]=[CH:37][CH:38]=1

Participants

3

Reactant 2

HCID 59636708HCID 59636708, compoundHCID 59636743N,N-dimethyl-7-(piperazin-1-yl)benzofuran-2-carboxamide

Product 1

HCID 59636722HCID 59636722, compound

Procedure

The compound was prepared according to the procedure disclosed in Example 46 starting from N,N-dimethyl-7-(piperazin-1-yl)benzofuran-2-carboxamide (0.085 g, 0.31 mmol) (Example 39d) and 2-(3-methoxypyridin-2-yl)ethyl 4-methylbenzenesulfonate (0.092 g, 0.31 mmol). The product was purified by preparative HPLC to give the title compound.

Workup

  1. customThe compound was prepared
  2. customThe product was purified by preparative HPLC

Sources & evidence

ORD record
ord-34086286ddc24119a0d6a469d5f1d492
Source dataset
uspto-grants-2014_10
Patent number
US08859534B2

Reaction notes

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