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HRID535735

反应详情

EQUATION

反应方程式

HRID 535735 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1cc(Cl)cc(Br)c1Cl
HCID18354554

1-Bromo-2,5-dichloro-3-nitrobenzene

C6H2BrCl2NO2

结构：CC1(C)OB(c2cccc(N)c2Cl)OC1(C)C
HCID58164432

2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

C12H17BClNO2

PRODUCTS

生成物

1
结构：Nc1cc(Cl)cc(Br)c1Cl
HCID18354530

未命名化合物

收率 24%

PROCEDURE

实验过程

This material was prepared according to the procedure used for SM-9, step 2 using 1-bromo-2,5-dichloro-3-nitrobenzene. Purification by flash chromatography (SiO2, 0-30% EtOAc in heptane) provided 3-bromo-2,5-dichloroaniline (24%): LCMS (m/z) 239.9 (MH+), tR=1.03 minutes; 1H NMR (400 MHz, CDCl3) δ 4.28 (br s, 2H) 6.71 (d, J=2.4 Hz, 1H) 7.02 (d, J=2.4 Hz, 1H).

WORKUP

后处理

  1. customThis material was prepared
  2. customPurification by flash chromatography (SiO2, 0-30% EtOAc in heptane)