HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-2-(4-(Benzyloxy)phenyl)cyclopropan-1-amine → (1R,2S)-2-(4-Bromophenyl)cyclopropan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-2-(4-(Benzyloxy)phenyl)cyclopropan-1-amine | HCID 51888238 | — |
| Reactant | 1-Bromo-4-[(trans)-2-nitrocyclopropyl]benzene | HCID 67064639 | — |
| Product | (1R,2S)-2-(4-Bromophenyl)cyclopropan-1-amine | HCID 36217788 | 10% |
Reaction Steps
This compound was synthesized using the same methodology described in Intermediate D, using as starting material 1-bromo-4-[(trans)-2-nitrocyclopropyl]benzene. 10% yield. 1HNMR (CD3OD): 1.45 (m, 2H), 2.61 (m, 1H), 2.86 (m, 1H), 6.98 (d, 2H), 7.11 (d, 2H). MS (M+H): 211.9
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859555B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-a8a3d0400e4e499ea7df1a549c3d19de |
| Source note | uspto-grants-2014_10 |