HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methyl-1H-imidazol-1-yl)-2-nitroaniline → 2-Amino-4-(4-methyl-1H-imidazol-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methyl-1H-imidazol-1-yl)-2-nitroaniline | HCID 86709559 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Amino-4-(4-methyl-1H-imidazol-1-yl)aniline | HCID 10058290 | 95.7% |
Reaction Steps
4-(4-Methyl-1H-imidazol-1-yl)-2-nitroaniline (0.22 g, 1 mmol) was suspended in 20 mL of anhydrous methanol. The mixture was reduced with 0.11 g of Raney Ni at 40 psi for 7 hrs. Then the Raney Ni was removed by filtration. The filtrate was evaporated to give the title compound 0.18 g as a yellow solid (95.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859553B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-a677589cb8e245c7a3429733a4c884ed |
| Source note | uspto-grants-2014_10 |