HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 535999Generated: November 1, 2026
HCID 67496708, compound → HCID 67497157, compound
https://huagongshe.com/reaction/535999
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 67496708 | HCID 67496708 | — |
| Catalyst | Chlorotris(triphenylphosphine)rhodium(I) | HCID 84599 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | HCID 67497157 | HCID 67497157 | 10.5% |
Reaction Steps
The above compound, 9-allyl-1-propyl-8-thiophen-2-yl-1,9-dihydro-purin-6-one (0.100 g, 0.33 mmol) and Wilkinson's catalyst were taken in acetonitrile:water (6:1, 7 ml) and refluxed for 5 h at 100° C. Solvent was removed and further purified by preparative TLC to get pure 1-propyl-8-thiophen-2-yl-1,7-dihydro-purin-6-one (9 mg, 10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08859566B2 |
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| Source dataset | uspto-grants-2014_10 |
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| ORD ID | ord-570f92346238489385f3ae0401c6a40d |
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| Source note | uspto-grants-2014_10 |
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