4-Chloro-6,7-dimethoxyquinazoline → HCID 68193733, compound

HRID 536072Notes

Reaction equation

HRID 536072 reaction equation
[Cl:1]C1C2C(=CC(OC)=C(OC)C=2)N=CN=1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][C:27]=1[O:28][CH3:29])[N:24]=[CH:23][N:22]=[C:21]2[NH:30][C:31]1[CH:32]=[C:33]([S:40]([NH:43][CH3:44])(=[O:42])=[O:41])[CH:34]=[CH:35][C:36]=1[N:37]([CH3:39])[CH3:38]>>[ClH:1].[CH3:16][O:17][C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][C:27]=1[O:28][CH3:29])[N:24]=[CH:23][N:22]=[C:21]2[NH:30][C:31]1[CH:32]=[C:33]([S:40]([NH:43][CH3:44])(=[O:42])=[O:41])[CH:34]=[CH:35][C:36]=1[N:37]([CH3:38])[CH3:39]

Participants

3

Reactant 2

HCID 27693644-Chloro-6,7-dimethoxyquinazolineHCID 52933152HCID 52933152, compound

Product 1

HCID 68193733HCID 68193733, compound

Procedure

The following compounds were prepared with procedures analogous to that described in Example 1 using 4-chloro-6,7-bis(methyloxy)quinazoline and the specified aniline as starting materials:

Workup

  1. customThe following compounds were prepared with procedures analogous to

Sources & evidence

ORD record
ord-d982691f028c4431a772a74e2ebede6e
Source dataset
uspto-grants-2014_10
Patent number
US08859571B2

Reaction notes

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