HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butyl 4-formylpiperidine-1-carboxylate → 1-Boc-4-[(2-Ethoxycarbonyl-1H-pyrrol-3-ylamino)methyl]piperidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | tert-Butyl 4-formylpiperidine-1-carboxylate | HCID 1514430 | — |
| Edukt | Ethyl 3-amino-1H-pyrrole-2-carboxylate | HCID 2773439 | — |
| Produkt | 1-Boc-4-[(2-Ethoxycarbonyl-1H-pyrrol-3-ylamino)methyl]piperidine | HCID 67068472 | 10% |
Reaktionsschritte
The title compound (0.156 g, 10%) was prepared in accordance with general method A starting from 3-amino-1H-pyrrole-2-carboxylic acid ethyl ester (0.68 g, 4.4 mmol) and 4-formylpiperidine-1-carboxylic acid tert-butyl ester (P. C. Ting et al., Bioorganic & Medicinal Chemistry Letters, 2001, 11, 491-494) (0.98 g, 4.6 mmol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08859568B2 |
| Quelldatensatz | uspto-grants-2014_10 |
| ORD ID | ord-497ee395dcef4a3a9eb985729d2a4e4d |
| Quellennotiz | uspto-grants-2014_10 |