HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 67068493, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Indole-3-Carboxaldehyde | HCID 10256 | — |
| Reactant | Ethyl 3-amino-1H-pyrrole-2-carboxylate | HCID 2773439 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67068493 | HCID 67068493 | — |
Reaction Steps
A reaction mixture of 3-amino-1H-pyrrole-2-carboxylic acid ethyl ester (0.075 g, 0.49 mmol), indole-3-carboxaldehyde (0.085 g, 0.58 mmol), NaCNBH3 (0.031 g, 0.49 mmol) and HOAc (0.056 mL, 0.97 mmol) in methanol (3 mL) was stirred at r.t. overnight. The mixture was concentrated in vacuo and the crude product-mixture was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859568B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-4e07a3aec3554498b56e1a0ae7bc7275 |
| Source note | uspto-grants-2014_10 |